Skin toxicity – Grade 2-4 – Low risk

Assessment and investigations

  • Perform anamnesis, clinical assessment, and basic lab test


Management escalation pathway

  • Treat ambulatory
  • Apply topical steroids as indicated
  • Apply symptomatic treatment to associated symptoms (e.g. itching, dry skin) as indicated second-generation antihistamines
  • If symptoms persist > 6 days consult dermatologist

Symptoms resolved to grade 0 or 1?


  • Stop topical therapy
  • Restart ICPI


  • biopsy should be done


BSA: Body Surface Area
ADL: Activities of Daily Living
BW: Body Weight
ICU: Intensive Care Unit