Uncomplicated Peripheral neuropathy – Mild

Management escalation pathway

  • Low threshold to withhold ICPI
  • Close monitoring for any progression

Assessment and Investigations

  • Comprehensive neurological examination
  • Autoimmune anamnesis alcohol history, medication – diabetic screen – B12/folate – HIV – TSH – autoimmune serology – alcohol stigmata
  • MRI brain or spine (exclude CVA, structural cause)
  • Lumbar puncture to exclude tumor invasion (after brain CT scan)
  • Contact neurologist.


CMV: Cytomegalovirus
CIDP: Chronic Inflammatory Demyelinating Polyneuropathy
GBS: Guillain Barré Syndrome
PJP: Pneumocystis Jirovei Pneumopathy