Colitis – Low Risk – Yes

The diarrhea stopped within 72h and no recurrence on day 4 and 5

  • Taper steroids every 5 days (provide taper plan on paper to the patient)
  • Control blood tests weekly until normal or return to baseline
  • In case or recurrence, treat according to medium risk management guidelines

ICPi might be resumed >1 week after stopping steroid therapy and in the absence of diarrhea/colitis recurrence (https://www.ncbi.nlm.nih.gov/pubmed/31163011)

Abbreviations

Abbrevations:

H: Hematology
C: Chemistry
ICPi: Immune Checkpoint Blockade Inhibition
Hb: Hemoglobin
CRP: C Reactive Protein
BP: Blood Pressure