Skin toxicity – Grade 2-4 – High risk
Assessment and investigations
- Perform biopsy
- Perform blood analysis
Management escalation pathway
- Hospitalize in ICU/burn unit
- Apply electrolyte and fluid control
- Apply nutritional control initiated antibiotic therapy as indicated
- Apply general burn unit measures (e.g. sterile handling, antiseptic solution, repeated cultures, pain management …)
- Withhold ICPI and consider other causes (treatment related, paraneoplastic, …)
- Instore systemic immunosuppression (corticoids and beyond)
Abbrevations
BSA: Body Surface Area
ADL: Activities of Daily Living
BW: Body Weight
ICU: Intensive Care Unit
