Did the diarrhea stop within 72h and no recurrence on day 4 and 5?

Yes

Taper steroids every 5 days (provide taper plan on paper to the patient) Control blood tests weekly until normal or return to baseline In case or recurrence, treat according to medium risk management guidelines

Resume ICPi >1 week aer stopping steroid therapy and in the absence of diarrhea/colitis recurrence

No

Treat according to medium risk management guidelines

Abbreviations

Abbrevations

H: Hematology
C: Chemistry
ICPi: Immune Checkpoint Blockade Inhibition
Hb: Hemoglobin
CRP: C Reactive Protein
BP: Blood Pressure