Silent Hypophysitis

Management escalation pathway

  • Await pituitary axis to confirm diagnosis, but warn patients to seek urgent review if he-she is feeling unwell
  • Continue ICPi with appropriate HRT
  • Discuss with endocrinologist


HRT: Hormone Replacement Therapy
ADL: Activities of Daily Living
SHBG: Sex Hormone Binding Globulin
CBG: Cortisol Binding Globulin
IGF-1: Insulin-like Growth Factor 1
GH: Growth Hormone
MRI: Magnetic Resonance Imaging