< 6 stools/day, abdominal pain, blood or mucus in stool
Withhold administration of ICPI
> 7 stools/day, peritoneal signs consistent with bowel perforation, ileus, fever
Perform anamnesis, physical examination, blood analysis (H, C, CRP), coproculture
Initiate oral methylprednisolone at a dose of 2x 32 mg per day, start first dose in hospital.
Initiate oral antibiotics (e.g. ciproxin 250 mg BID) in case of suspected infectious origin and adapt according to result of coproculture